From bugweed to breakthroughs – PhD explores the hidden power of medicinal plants

Dr Myuri Parusnath’s research into plant-based bioactive compounds has earned her a PhD in biology from the University of KwaZulu-Natal (UKZN).

Parusnath’s study of Solanum mauritianum, commonly known as bugweed, explored the potential medicinal value of a plant that is often overlooked.

Parusnath spoke about her research, titled ‘Secretory, Phytochemical and Biological Activities of Solanum mauritianum Scop. (Solanaceae)’.

Although bugweed is classified as an invasive species in South Africa, plants that thrive so successfully in diverse environments often possess complex chemical defence systems, many of which may have medicinal value.

“In this study, I investigated the microscopic structures of the plant, analysed its chemical composition and evaluated several biological activities, including antioxidant, antibacterial and cytotoxic properties. The aim was to explore whether this plant could serve as a potential source of natural bioactive compounds. This research is particularly relevant in the context of growing antibiotic resistance and the need for alternative therapeutic options. In many parts of the world, medicinal plants remain an important component of healthcare, and scientific studies such as this help validate and expand our understanding of their potential applications,” she said.

Parusnath’s interest in the field is rooted in a longstanding curiosity about science and the natural world.

Always fascinated by how biological systems function and how research can uncover new insights, the possibility of exploring plants as sources of biologically active compounds and contributing to discoveries that might one day support therapeutic development strongly motivated her work.

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Her research adds to a growing body of knowledge about plant-derived compounds and their potential value.

“By examining the chemical composition and biological activity of Solanum mauritianum, my research helps build a scientific foundation that future studies can expand upon, particularly in the search for plant-based therapeutic agents,” she explained.

Beyond her doctoral research, Parusnath remains actively involved in academic life and student development.

She serves as a first-year experience (FYE) co-ordinator within the College of Agriculture, Engineering and Science and works as a part-time lecturer in Biology within the School of Agriculture and Science. 

Long-term, she aspires to build a career in academia and research while mentoring and supporting future generations of students.

Parusnath credited several people who helped her reach this milestone, including her supervisor, Professor Yougasphree Naidoo, and co-supervisor, Professor Moganavelli Singh, who mentored and guided her through both her master’s and doctoral studies.

She also expressed deep gratitude to her parents, brother and friends for their unwavering support.

Despite the demands of doctoral study, Parusnath emphasised the importance of maintaining balance. In her spare time, she enjoys going to the gym, exploring creative interests such as makeup and spending time with friends and family.

Reflecting on the broader significance of her achievement, Parusnath hopes her journey will inspire others, particularly young women considering careers in science. 

“Doctoral graduates represent a small proportion of the global population, and women remain underrepresented in many scientific fields. Through my work and example, I hope to encourage more women to pursue paths in science, research and higher education,” she concluded.